第三届全球(长春)制造业服务外包峰会

李文保

李文保

深圳华大海洋科技有限公司首席科学家

嘉宾简介

博士、教授、博士生导师。国家特聘专家,国家海洋实验室鳌山人才卓越科学家,山东省泰山学者海外特聘专家,青岛市创新领军人才。曾任中国海洋大学筑峰工程教授,青岛海洋生物医药研究院首席科学家兼副院长。


1990年中科院化学博士,美国Rice大学和威斯康星大学博士后。先后在美国诺华和位于加州圣地亚哥的IRORI/ChemRx/DPI药物技术公司从事新药及其技术开发十多年,具有25年以上的工作经验及相应的管理经验。在药物化学、有机化学、天然产物化学,尤其是在先导化合物/候选药物的设计合成、筛选、结构优化等方面具有丰富的经验。研究领域包括抗肿瘤、抗糖尿病及治疗心血管和神经退行性疾病等药物的研发,其中作为主要研究人员开发成功的抗糖尿病抗肥胖症的候选药物被诺华公司以1.57亿美元买断并进入临床实验。2007年回国后主要从事具有自主知识产权抗肿瘤一类新药的开发,其中候选药物SL01获国家“十一五”和“十二五”重大新药创制科技重大专项资金支持,现已完成临床前研究。从2014年至今,致力于具有海洋特色生物活性分子的结构优化、成药性及临床前研究。其中CMBT-001(MBRI-001)项目已进入系统临床前研究。迄今,已获得二十多项国内外发明专利授权,发表了50多篇SCI文章。2010年荣获山东省“齐鲁友谊”奖。


Wenbao LI

Chief Scientist in Shenzhen Huada Ocean Scientific and Technology Company

Doctor, Professor, doctoral supervisor. He is national special experts, National Marine Laboratory Aoshan talent scientists, Shandong Taishan scholars, Qingdao innovation leading talents. He was a professor of "Building Peak Talents Project" of Ocean University of China and chief scientist and vice president of Marine Biomedical Research Institute of Qingdao.

He has worked in Novartis and Irori / Chemrx / DPI pharmaceutical technology company in San Diego, California for more than 10 years, with more than 25 years of working experience and corresponding management experience. He has rich experience in pharmaceutical chemistry, organic chemistry, natural product chemistry, especially in the design, synthesis, screening and structural optimization of lead compounds / candidate drugs. His research fields include antitumor, anti-diabetes and drug therapy for cardiovascular and neurodegenerative diseases. So far, he has obtained more than 20 domestic and foreign invention patent authorization and published more than 50 SCI articles.